Cellular Generation and Phenotyping
Wellcome Trust Sanger Institute

The integrated phenotyping suite was the largest in Europe on completions supporting large-scale research involving the sequencing of genetic material. This project creates 670sqm of wet laboratories, including CL2 and CL3 labs and 200sqm of administration space.

The suite required modification of circulation routes within the existing building which presented a construction challenge in keeping complex adjacent facilities in operation throughout the works.

The Cellular Generation and Phenotyping (CGaP) core facility provides central cell biology support to the Institute, in particular the scale-up and automation of existing protocols to facilitate ‘Science at Scale’.

The group has expertise in cell derivation from primary tissue, iPS derivation, cellular differentiation, phenotypic assays (e.g. high content imaging) and end point analysis (e.g. ELISA), and Luminex and functional bioassays.